BAG4 anticorps (C-Term)

N° du produit ABIN2799014

L’anticorps Lapin Polyclonal anti-BAG4 a été validé pour WB. Il convient pour détecter BAG4 dans des échantillons de Humain.

Aperçu rapide pour BAG4 anticorps (C-Term) (ABIN2799014)

Antigène: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAG4 anticorps

Épitope: AA 381-409, C-Term

Fonction: Rabbit Anti-Human BAG4 (C-term) Antibody

Immunogène: This BAG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-409 amino acids from the C-terminal region of human BAG4.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000BAG4 Antibody (C-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur BAG4

Antigène: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Autre désignation: BAG4

Sujet:

Target Description: BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.

Gene Symbol: BAG4

Poids moléculaire: 49594 Da

ID gène: 9530

UniProt: O95429

Pathways: Regulation of Actin Filament Polymerization